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Renal Cell Carcinoma

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November 07, 2022
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Trials for advanced renal cell carcinoma often use restrictive eligibility criteria

Trials for advanced renal cell carcinoma often use restrictive eligibility criteria

Many contemporary clinical trials for metastatic renal cell carcinoma incorporate restrictive eligibility criteria, according to study results.

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November 06, 2022
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Artificial intelligence may help predict cardiotoxicity in renal cell carcinoma

Artificial intelligence may help predict cardiotoxicity in renal cell carcinoma

Artificial intelligence models can help predict cardiotoxicity risk among patients with renal cell carcinoma treated with VEGF receptor inhibitors, according to study results.

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November 05, 2022
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End-stage renal disease after renal cell carcinoma linked to shorter survival

End-stage renal disease after renal cell carcinoma linked to shorter survival

Risk for new-onset end-stage renal disease is considerably higher after treatment for renal cell carcinoma, according to results of a nationwide population-based study.

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November 04, 2022
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Exercise linked to better mental, physical health among those with kidney cancer

Exercise linked to better mental, physical health among those with kidney cancer

Physical activity or exercise appeared associated with improved mental and physical health among people with kidney cancer, according to study results.

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September 26, 2022
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Immunotherapy combo fails to extend disease-free survival in high-risk kidney cancer

Immunotherapy combo fails to extend disease-free survival in high-risk kidney cancer

The combination of nivolumab and ipilimumab after nephrectomy failed to extend DFS among patients with localized renal cell carcinoma at high risk for relapse, results of the phase 3 CheckMate 914 trial showed.

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September 12, 2022
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Cabozantinib regimen ‘beat the doublet in PFS’ in untreated advanced kidney cancer

Cabozantinib regimen ‘beat the doublet in PFS’ in untreated advanced kidney cancer

Cabozantinib plus nivolumab and ipilimumab conferred a significant PFS benefit vs. nivolumab and ipilimumab alone among patients with advanced renal cell carcinoma, according to results of the COSMIC-313 trial presented at ESMO Congress.

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August 22, 2022
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Major adverse cardiovascular event risk higher with targeted therapies for kidney cancer

Major adverse cardiovascular event risk higher with targeted therapies for kidney cancer

Targeted cancer therapy had a higher association with risk for major adverse cardiovascular events than cytokine therapy among patients with advanced renal cell carcinoma, according to study results.

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July 29, 2022
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Nivolumab-ipilimumab fails to show DFS benefit for certain patients with kidney cancer

Part A of a phase 3 trial assessing adjuvant nivolumab and ipilimumab for certain patients with renal cell carcinoma failed to meet the primary endpoint of DFS, according to topline data released by the agents’ manufacturer.

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June 22, 2022
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Quality of life associated with survival in RCC

CHICAGO — Better health-related quality of life was linked to longer survival in patients with intermediate- or poor-risk renal cell carcinoma, according to an analysis of the CheckMate 214 trial.

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June 21, 2022
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Deeper treatment response linked to improved survival in advanced renal cell carcinoma

CHICAGO — Deeper response to treatment was associated with improved progression-free and overall survival in patients with advanced renal cell carcinoma, according to data from the CheckMate 9ER trial.

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