Remission

A man has remained in treatment-free HIV remission for nearly 2 years after receiving a stem-cell transplant to treat a rare and aggressive form of leukemia, researchers reported Wednesday.

In patients with systemic lupus erythematous, CAR T-cell therapy appears to be a feasible and effective method of achieving durable remission, according to a speaker at the Biologic Therapies Summit.

CHICAGO — Biologic-naive patients treated with vedolizumab and ustekinumab for Crohn’s disease had similar rates of clinical response and remission, although mucosal healing and biologic treatment persistence differed at 36 months.

DESTIN, Fla. — Low disease activity and remission are achievable for patients with lupus if clinicians “minimize the prednisone” and administer adequate hydroxychloroquine, noted a speaker at the 2023 Congress of Clinical Rheumatology-East.

Calorie-restricted diets, particularly in conjunction with an intensive lifestyle modification program, were associated with increased remission rates among patients with type 2 diabetes, according to a meta-analysis of 28 randomized trials.

A computer-aided diagnosis system successfully distinguished disease remission from activity and predicted the risk for subsequent flare among patients with ulcerative colitis, according to results published in Gastroenterology.

For individuals diagnosed with treatment-resistant depression, response and remission rates for IV ketamine and intranasal esketamine were similar, but remission time was quicker with the former compared with the latter.

Increasing adalimumab dose intervals reduced infection-related adverse events and costs in patients with Crohn’s disease, but also resulted in lower remission rates, researchers reported in The Lancet Gastroenterology & Hepatology.

Patients with systemic lupus erythematosus receiving anifrolumab are more likely to achieve earlier, more frequent and longer low disease activity, compared with those taking placebo, according to data.

Remission should be the primary goal for patients with childhood-onset systemic lupus erythematosus, according to new points to consider for treat-to-target endorsed by the Pediatric Rheumatology European Society.