Remission
Positive results announced in phase 2a trial of take-home microdosing drug for depression
MindBio Therapeutics has announced positive topline results from its take-home phase 2a clinical trial of MB22001 in patients with depression, according to a company press release.
SLE-DAS remission, low disease activity show promise as treat-to-target measures
Remission and low disease activity can discriminate between patients taking active drug vs. placebo in clinical trials and are linked to health-related quality of life, according to data in Arthritis Care & Research.
Biomarkers might predict asthma remission after anti-IL-5 therapy
Sputum neutrophil percentage and levels of eotaxin-1, IL-5 and eosinophil peroxidase may be used to predict remission among patients with severe asthma 1 year after anti-IL-5 therapy, according to a study published in CHEST.
Revumenib trial meets complete remission endpoint for acute leukemia subsets
Revumenib conferred complete remission or complete remission with partial hematologic recovery in nearly one-quarter of patients with two acute leukemia subtypes, according to the agent’s manufacturer.
Workgroup releases consensus definition for clinical remission in asthma on treatment
A multi-organizational panel has developed a working definition for clinical remission in asthma, according to a paper published in Annals of Allergy, Asthma & Immunology.
Clinical remission of severe asthma ‘achievable goal’ with mepolizumab
Patients with severe asthma achieved clinical remission based on a four-component definition with 52 weeks of mepolizumab, according to an abstract presented at the European Respiratory Society International Congress.
Most adults with Cushing’s disease achieve remission with ketoconazole after surgery
Most adults with Cushing’s disease who received ketoconazole after transsphenoidal surgery had a reduction in cortisol to normal levels, according to findings published in Frontiers in Endocrinology.
Patients with low RA activity more likely to stay in remission after switch to monotherapy
Patients with rheumatoid arthritis who demonstrate lower disease activity are more likely to remain in LDA or remission after switching from combination therapy to monotherapy, according to data published in the Journal of Rheumatology.
Man remains in treatment-free HIV remission after stem cell transplant
A man has remained in treatment-free HIV remission for nearly 2 years after receiving a stem-cell transplant to treat a rare and aggressive form of leukemia, researchers reported Wednesday.
B-cell system reset in CAR T-cell therapy ‘feasible,’ leads to durable remission in lupus
In patients with systemic lupus erythematous, CAR T-cell therapy appears to be a feasible and effective method of achieving durable remission, according to a speaker at the Biologic Therapies Summit.