Remission

SAN DIEGO — Few patients are evaluated based on all seven endpoints of guidelines indicating complete asthma remission, according to a poster presented at the American Thoracic Society International Meeting.

DESTIN, Fla. — Rheumatologists should consider tapering tocilizumab for patients with giant cell arteritis in remission despite the increased risk for flare, said a speaker at the Congress of Clinical Rheumatology East annual meeting.

Patients in rheumatoid arthritis remission who tapered off conventional synthetic disease-modifying antirheumatic drugs had higher risks for flares, with two methods failing to reach non-inferiority vs. stable dosage, according to data.

DENVER — Four children born with HIV who initiated ART within 48 hours of delivery later remained in treatment-free remission for over a year after ART was paused, researchers reported.

MindBio Therapeutics has announced positive topline results from its take-home phase 2a clinical trial of MB22001 in patients with depression, according to a company press release.

Remission and low disease activity can discriminate between patients taking active drug vs. placebo in clinical trials and are linked to health-related quality of life, according to data in Arthritis Care & Research.

Sputum neutrophil percentage and levels of eotaxin-1, IL-5 and eosinophil peroxidase may be used to predict remission among patients with severe asthma 1 year after anti-IL-5 therapy, according to a study published in CHEST.

Revumenib conferred complete remission or complete remission with partial hematologic recovery in nearly one-quarter of patients with two acute leukemia subtypes, according to the agent’s manufacturer.

A multi-organizational panel has developed a working definition for clinical remission in asthma, according to a paper published in Annals of Allergy, Asthma & Immunology.

Patients with severe asthma achieved clinical remission based on a four-component definition with 52 weeks of mepolizumab, according to an abstract presented at the European Respiratory Society International Congress.