Remission

Patients in rheumatoid arthritis remission who tapered off conventional synthetic disease-modifying antirheumatic drugs had higher risks for flares, with two methods failing to reach non-inferiority vs. stable dosage, according to data.

DENVER — Four children born with HIV who initiated ART within 48 hours of delivery later remained in treatment-free remission for over a year after ART was paused, researchers reported.

MindBio Therapeutics has announced positive topline results from its take-home phase 2a clinical trial of MB22001 in patients with depression, according to a company press release.

Remission and low disease activity can discriminate between patients taking active drug vs. placebo in clinical trials and are linked to health-related quality of life, according to data in Arthritis Care & Research.

Sputum neutrophil percentage and levels of eotaxin-1, IL-5 and eosinophil peroxidase may be used to predict remission among patients with severe asthma 1 year after anti-IL-5 therapy, according to a study published in CHEST.

Revumenib conferred complete remission or complete remission with partial hematologic recovery in nearly one-quarter of patients with two acute leukemia subtypes, according to the agent’s manufacturer.

A multi-organizational panel has developed a working definition for clinical remission in asthma, according to a paper published in Annals of Allergy, Asthma & Immunology.

Patients with severe asthma achieved clinical remission based on a four-component definition with 52 weeks of mepolizumab, according to an abstract presented at the European Respiratory Society International Congress.

Most adults with Cushing’s disease who received ketoconazole after transsphenoidal surgery had a reduction in cortisol to normal levels, according to findings published in Frontiers in Endocrinology.

Patients with rheumatoid arthritis who demonstrate lower disease activity are more likely to remain in LDA or remission after switching from combination therapy to monotherapy, according to data published in the Journal of Rheumatology.