Radiotherapy

Primary transoral robotic surgery appeared associated with greater risk for short-term dysphagia compared with primary radiotherapy or chemoradiotherapy among patients with T1-T2 oropharyngeal squamous cell carcinoma, study results showed.

Treatment for anal cancer has advanced significantly over the years, but the standard radiotherapy regimen used regardless of tumor size has led to various immediate and long-term adverse events.

In this video, Joshua Brody, MD, discusses the results of the IELSG37 randomized trial, which examined whether radiotherapy is necessary after front-line chemoimmunotherapy for patients with primary mediastinal B-cell lymphoma.

The addition of stereotactic body radiotherapy to immune checkpoint inhibitors failed to significantly extend survival among individuals with advanced solid tumors, results of the randomized phase 2 CHEERS trial showed.

In this edition, surgery confers higher 5-year survival rates than radiotherapy; first-line combination extends PFS in lung cancer subgroup; pembrolizumab improves outcomes in early-stage resectable lung cancer, and more.

CHICAGO — Radiation therapy can be safely omitted for patients with primary mediastinal B-cell lymphoma who demonstrate a complete metabolic response after chemoimmunotherapy, according to data presented at ASCO Annual Meeting.

Prolonged radiotherapy duration appeared associated with inferior DFS among a cohort of patients with esophageal cancer, according to study results published in JAMA Network Open.

In this edition, ‘paradigm shift’ in non-small cell lung cancer during past decade; osimertinib extends survival in early EGFR-mutated NSCLC; amivantamab shows durable activity in patients with advanced NSCLC, and more.

Patients with limited-stage small cell lung cancer who received higher-dose, once-daily radiotherapy achieved outcomes comparable to those who received the standard lower-dose, once-daily regimen, according to phase 3 study results.

Men with localized prostate cancer exhibited low risk for disease-specific mortality regardless of their assigned treatment, according to study results published in The New England Journal of Medicine.