Radiation Therapy

Patients who survived cancer have an increased risk for mortality from CHD and stroke compared with the general population, according to a study published in the European Heart Journal.

The superoxide dismutase mimetic GC4419 appeared to safely and significantly reduce the duration, incidence and severity of radiation-induced severe oral mucositis compared with placebo among patients with head and neck cancer, according to results of a randomized phase 2b study published in Journal of Clinical Oncology.

Patients who received radiation therapy before chimeric antigen receptor T-cell therapy for relapsed or refractory non-Hodgkin lymphoma were less likely to have severe treatment-related toxicities, according to results of a study presented at the American Society of Radiation Oncology Annual Meeting.

The addition of stereotactic body radiotherapy after progression on pembrolizumab prolonged PFS among patients with metastatic non-small cell lung cancer, according to results of a prospective phase 2 study presented during the plenary session of American Society for Radiation Oncology Annual Meeting.

Balancing long-term risks and benefits of potentially toxic therapies, while achieving a cure, remains a delicate challenge in cancer treatment.

Historically, HER2-positive breast cancers have been among the most challenging to treat. These cancers generally grow and spread more quickly than other subtypes of breast cancer. They also correlate with a worse prognosis.

Patients with oropharyngeal cancer undergoing radiation therapy experienced delayed initiation of narcotic use for pain from mucositis when treated with gabapentin, according to study results presented at the 2014 Oncology Nursing Society Annual Congress.

Reduced radiation treatment volume to the submandibular lymph nodes was associated with improved patient-reported salivary function in a cohort of patients with node-positive oropharyngeal carcinoma, according to study results presented at the Multidisciplinary Head and Neck Cancer Symposium.

Sparing the contralateral submandibular gland with low doses of radiation therapy appeared safe and effective among patients with locally advanced head and neck cancers, according to study results presented at the Multidisciplinary Head and Neck Cancer Symposium.