Puberty

Anogenital lichen sclerosus can lead to permanent anatomical changes and sexual discomfort in women, highlighting a need for long-term follow-up and high treatment adherence, the latter of which is lacking, according to a study.

Some types of endocrine-disrupting chemicals may act as kisspeptin or gonadotropin-releasing hormone receptor agonists and could induce early puberty for children, according to in vitro findings published in Endocrinology.

Higher acne vulgaris prevalence was associated with puberty status, skin of color and weight gain among adolescents, according to a study.

Children and adolescents with a high polygenic risk score for polycystic ovary syndrome tend to have a higher BMI and are more likely to develop obesity, according to study data.

Patients with epidermolysis bullosa are at risk for delayed puberty, which can have a significant impact on bone mineral density, according to a study, and this is especially true of those with recessive dystrophic epidermolysis bullosa.

Serum levels of sex steroids and bone metabolism markers align with skeletal development in boys during puberty, though development can vary based on pubertal stage, according to study findings published in Bone.

Distinct patterns of early life weight gain predict differential risk for earlier onset of puberty among girls, according to data from a longitudinal analysis published in Journal of the Endocrine Society.

Researchers found a decrease in depression and suicidality among transgender and non-binary youth receiving puberty blockers or gender-affirming care, according to a presentation at the AAP National Conference & Exhibition.

For care with nonbinary children, there are no guidelines, there is very little experience, and all the knowledge we have is anecdotal. There is also not enough research.

In a little more than a decade, access to gender-affirming care for minors has increased greatly across the U.S.