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Psychosis

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November 30, 2023
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Phase 2 study of Alzheimer’s disease psychosis therapy initiated

Phase 2 study of Alzheimer’s disease psychosis therapy initiated

A phase 2 clinical trial has been initiated to evaluate the safety and efficacy of an inverse agonist for hallucinations and delusions associated with Alzheimer’s disease psychosis, according to the manufacturer.

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Targeting Novel Pathways to Address Unmet Needs in Schizophrenia Treatment

Targeting Novel Pathways to Address Unmet Needs in Schizophrenia Treatment
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August 17, 2023
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Psychological therapy can improve sleep in young people at ultra-high risk for psychosis

Psychological therapy can improve sleep in young people at ultra-high risk for psychosis

A psychological sleep intervention reduced severity of insomnia and mental health symptoms as early as 3 months in young people at ultra-high risk for psychosis and warrants further study, according to research in The Lancet Psychiatry.

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July 08, 2023
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Sequence, timing of HF, diabetes, psychosis have ‘complex’ effect on long-term mortality

Sequence, timing of HF, diabetes, psychosis have ‘complex’ effect on long-term mortality

Adults who developed diabetes, psychosis and congestive HF, in that order, had reduced life expectancy compared with people who developed the same three conditions in a different order, researchers reported.

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June 30, 2023
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Innovation needed in relapse prevention for those with ultrahigh risk of psychosis

Innovation needed in relapse prevention for those with ultrahigh risk of psychosis

Existing treatments for patients with an ultrahigh risk of psychosis offer relatively poor responsiveness, underscoring a need for further innovation in relapse prevention, according to a study published in JAMA Psychiatry.

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January 30, 2023
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Impaired motor skills may indicate psychosis for kids in families with psych disorders

Impaired motor skills may indicate psychosis for kids in families with psych disorders

In children with familial high risk of schizophrenia or bipolar disorder, evidence of motor impairment skills may indicate neurodevelopmental vulnerability for psychosis.

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January 18, 2023
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Sleep disturbances prevalent during psychosis

Sleep disturbances prevalent during psychosis

Sleep disturbances were found to be prevalent throughout the course of psychosis, and different psychosis stages showed shared and distinct abnormalities, researchers reported in JAMA Psychiatry.

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November 07, 2022
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Prediction tools can be developed for those with first-episode psychosis

Prediction tools can be developed for those with first-episode psychosis

Accurate prediction tools can be developed for people with first episodes of psychosis, which could potentially help clinician decision-making, researchers reported in JAMA Psychiatry.

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August 09, 2022
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Environment plays larger role than genetics for psychotic experiences in adolescents

Environment plays larger role than genetics for psychotic experiences in adolescents

Environmental factors play a greater role in the genesis of psychotic experiences than genetic factors among adolescents, according to a study published in JAMA Psychiatry.

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August 05, 2022
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FDA rejects expanded use of Nuplazid for Alzheimer’s-related psychosis

FDA rejects expanded use of Nuplazid for Alzheimer’s-related psychosis

The FDA has declined to approve a supplemental new drug application for the expanded use of Nuplazid to treat psychosis related to Alzheimer's disease.

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