Proton Pump Inhibitor

Proton pump inhibitors may be associated with pharmacovigilance signals for the occurrence of drug-induced lupus erythematosus, according to a research letter published in JAMA Dermatology.

A recent meta-analysis revealed a significant association between proton pump inhibitor use and gastric and liver cancer.

The use of acid suppressants among children may increase their risks for incident asthma, atopic dermatitis and allergic rhinitis, according to a systematic review published in The Journal of Allergy and Clinical Immunology: In Practice.

GENEVA — Exposure to proton pump inhibitors appeared associated with increased risk for certain cancers, according to results of a meta-analysis presented at World Cancer Congress.

The AGA has released a clinical practice update and expert review on the characterization and management of patients with short bowel syndrome, which recently was published in Clinical Gastroenterology and Hepatology.

During the International Liver Congress, researchers presented 48-week trial data that showed once-weekly Ozempic improved cardiometabolic markers but not liver fibrosis in patients with nonalcoholic steatohepatitis and compensated cirrhosis.

LONDON — Exposure to proton pump inhibitors correlated with an increased risk for severe infection and cirrhosis decompensation among a subset of patients with cirrhosis, according to research presented at the International Liver Congress.

Concomitant proton pump inhibitor plus ticagrelor monotherapy after PCI does not increase risk for all-cause death or an adverse CV event, in contrast with conventional post-PCI antiplatelet therapy, researchers reported.

Although proton pump inhibitors were linked with an increased risk for infection and decompensation in patients with cirrhosis, they may still be of benefit in those with prior gastrointestinal bleeding, according to published data.

As proton pump inhibitors are being increasingly used for “less clear indications and indeterminate durations,” the American Gastroenterological Association announced a clinical practice update on deprescribing the agents in certain patients.