Proton Pump Inhibitor

Baseline concomitant exposure to commonly used medications, such as corticosteroids and 5-aminosalicylates, did not significantly affect clinical and endoscopic outcomes during induction therapy in ulcerative colitis, data analysis showed.

“Aggressive” combination therapy for gastroesophageal reflux disease improved survival among patients with systemic sclerosis and interstitial lung disease, according to data published in Arthritis Research & Therapy.

A pharmacy-based, multicomponent intervention program reduced proton pump inhibitor use overall and also when appropriate for gastroprotection, with little evidence of either clinical harms or benefits, according to a study in BMJ.

Vonoprazan was noninferior to high-dose IV proton pump inhibitor therapy in preventing 30-day rebleeding among patients with high-risk peptic ulcer bleeding who had achieved endoscopic hemostasis, according to data.

WASHINGTON — Infants who were exposed to acid-suppressive medications had increased risk for developing food allergy, according to an abstract presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.

Kidney transplant recipients who use proton pump inhibitors may experience increased fatigue and a reduced health-related quality of life, according to recently published data.

The use of proton pump inhibitors improves overall and progression-free survival in patients with systemic sclerosis-associated interstitial lung disease, according to data published in Rheumatology.

Drugs designed to treat heartburn may also help with tuberculosis by accelerating the treatment process, according to study results published in Proceedings of the National Academy of Sciences.

Adults with type 2 diabetes who use proton pump inhibitors have a higher risk for coronary artery disease, myocardial infarction, heart failure and all-cause mortality than nonusers, according to data from the UK Biobank.

In this edition, NCI director announces breast cancer diagnosis, neoadjuvant chemotherapy regimen in pancreatic cancer, gender harassment is in oncology and more.