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Prostate Cancer

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February 17, 2023
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Phase 3 trial of pembrolizumab for prostate cancer misses endpoints

Phase 3 trial of pembrolizumab for prostate cancer misses endpoints

SAN FRANCISCO — The addition of pembrolizumab to docetaxel failed to significantly extend survival for men with chemotherapy-naive metastatic castration-resistant prostate cancer, according to results of the randomized phase 3 KEYNOTE-921 trial.

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February 17, 2023
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Long-term ADT does not improve outcomes in high-risk prostate cancer

Long-term ADT does not improve outcomes in high-risk prostate cancer

SAN FRANCISCO — Long-term androgen deprivation therapy as part of tri-modality therapy did not improve outcomes for men with localized high-risk prostate cancer, according to randomized phase 3 study results.

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February 16, 2023
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Rucaparib improves radiographic PFS in prostate cancer subgroup

Rucaparib improves radiographic PFS in prostate cancer subgroup

SAN FRANCISCO — Rucaparib significantly improved radiographic PFS compared with physician’s choice of therapy for men with chemotherapy-naive metastatic castration-resistant prostate cancer, according to randomized phase 3 study results.

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February 16, 2023
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Talazoparib regimen improves outcomes among certain men with metastatic prostate cancer

Talazoparib regimen improves outcomes among certain men with metastatic prostate cancer

SAN FRANCISCO — The addition of talazoparib to first-line enzalutamide extended imaging-based PFS among men with metastatic castration-resistant prostate cancer, according to results of the randomized phase 3 TALAPRO-2 study.

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February 16, 2023
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Multimodal AI biomarker may help personalize decision-making in high-risk prostate cancer

Multimodal AI biomarker may help personalize decision-making in high-risk prostate cancer

SAN FRANCISCO — An artificial intelligence-derived biomarker enabled improved risk stratification for men with high-risk prostate cancer, according to study results presented at ASCO Genitourinary Cancers Symposium.

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January 12, 2023
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Cancer mortality declines 33% in past 30 years; prostate cancer cases on the rise

Cancer mortality declines 33% in past 30 years; prostate cancer cases on the rise

Cancer mortality in the United States has declined by 33% since 1991, according to an American Cancer Society report released today.

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January 11, 2023
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Social factors linked to disparities in prostate cancer outcomes among Black vs. white men

Social factors linked to disparities in prostate cancer outcomes among Black vs. white men

A relationship between race and social determinants of health contributed to significantly higher prostate cancer-specific morality among Black men in the United States, results of a meta-analysis in JAMA Network Open showed.

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January 06, 2023
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PCPs often order low-value prostate cancer screenings, study finds

PCPs often order low-value prostate cancer screenings, study finds

Primary care providers frequently order prostate cancer screenings for older patients, even when they provide little value and could lead to false-positive results, a recent study found.

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January 05, 2023
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Black men in U.S. face significantly higher prostate cancer incidence, related mortality

Black men in U.S. face significantly higher prostate cancer incidence, related mortality

Black men have the highest rates of prostate cancer incidence and related mortality compared with all other racial and ethnic groups among U.S.-based men, results of an analysis published in European Urology showed.

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December 27, 2022
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Prostate cancer 2022: AI-guided therapy and a new standard in high-risk disease

Prostate cancer 2022: AI-guided therapy and a new standard in high-risk disease

Several novel treatment regimens for prostate cancer emerged during the past year.

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