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Prostaglandin

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August 29, 2024
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NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition

NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition

In the third episode of the NSAIDs saga, we focus on COX-2 inhibition! Did the hopes and dreams of selective COX-2 inhibition pan out? What can the rise and fall of VIOXX teach us about physiology?

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June 26, 2024
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NSAIDs, Part 2: The Dawn of the Anti-Inflammatories

NSAIDs, Part 2: The Dawn of the Anti-Inflammatories

In this episode, we dive into the story of aspirin and the development of ibuprofen, ending with the experiments that showed the mechanism of how aspirin actually works.

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May 16, 2024
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The Discovery of Non-Steroidal Anti-inflammatory Drugs (NSAIDs), Part 1

The Discovery of Non-Steroidal Anti-inflammatory Drugs (NSAIDs), Part 1

Humans have had an insatiable appetite for inhibiting production of prostaglandins for centuries! This series delves into the history of aspirin and NSAIDs, looking at the understanding of the prostaglandin pathway.

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May 23, 2022
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Speaker: Prostaglandins, SLT good first-line treatment choices for glaucoma

NEW YORK – Either a prostaglandin or selective laser trabeculoplasty is an effective primary treatment for glaucoma, “but once you get past the primary therapy, there are 44,000 different combinations of glaucoma medications you can prescribe,” said a speaker here at Vision Expo East.

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January 23, 2020
1 min read
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Unregulated cosmetics contribute to ocular surface disease

Unregulated cosmetics contribute to ocular surface disease

KOLOA, Hawaii — A person who uses beauty products containing prostaglandins around their eyes and eyelashes may be spending a lot of money to contribute to their own dry eye, Laura M. Periman, MD, said at Hawaiian Eye 2020.

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January 20, 2020
2 min read
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Original, generic PGAs show no significant difference in IOP, tolerability

No significant difference was seen in efficacy and safety of prostaglandin analogues when comparing original and generics, according to a systematic review published in Ophthalmology Glaucoma.

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December 04, 2019
1 min read
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Aerie seeks European marketing authorization for Roclanda

Aerie Pharmaceuticals has submitted a marketing authorization application for Roclanda to the European Medicines Agency, according to a press release.