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Primary Immune Complex Membranoproliferative Glomerulonephritis

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November 07, 2024
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Pegcetacoplan may lower proteinuria substantially in C3 glomerulopathy

SAN DIEGO — Pegcetacoplan may offer a clinical strategy to stabilize kidney function and reduce proteinuria significantly for patients with C3 glomerulopathy or primary immune complex membranoproliferative glomerulonephritis, data show.

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August 09, 2024
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Phase 3 results for pegcetacoplan show reduced proteinuria, stabilized eGFR vs. placebo

Sobi and Apellis Pharmaceuticals Inc. announced results from the phase 3 Valiant study showing the drug pegcetacoplan reduced proteinuria and stabilized eGFR compared to placebo in patients with glomerulopathy or glomerulonephritis.