Pouchitis

Vedolizumab not only induced endoscopic improvements in patients with chronic pouchitis, but also appeared to improve clinical outcomes at week 34, especially in those who achieved mucosal healing at week 14, research showed.

The FDA has granted orphan drug designation to PharmassêtX’s PSX-514, a drug derived from an active component of green tea, for the treatment of pouchitis, according to a company press release.

Although effective in select patients, the AGA advised against fecal microbiota-based therapies to prevent recurrent Clostridioides difficile infection in severely immunocompromised adults or to treat other gastrointestinal conditions.

The AGA has published the first comprehensive guideline on the management of pouchitis and other inflammatory pouch disorders among patients with ulcerative colitis who have undergone ileal pouch-anal anastomosis surgery.

DENVER — A varied and well-balanced diet plays “a significant role” in the management of patients with inflammatory bowel disease and can be guided with support from a dietitian, a presenter reported at the Crohn’s and Colitis Congress.

Among patients with ulcerative colitis, IV vedolizumab safely and effectively treated chronic pouchitis following ileal pouch-anal anastomosis, according to research presented at the Congress of European Crohn’s and Colitis Organization.

Current or past smoking was not associated with increased risk for the development of pouchitis in patients with ulcerative colitis, according to a meta-analysis published in Alimentary Pharmacology & Therapeutics.

In newly issued guidelines, the American Gastroenterological Association did not recommend using probiotics for most digestive conditions.

AUSTIN, Texas — In this exclusive video from Crohn’s & Colitis Congress, Edward L. Barnes, MD, MPH, assistant professor of medicine at the University of North Carolina at Chapel Hill, discusses the results of a study he and colleagues presented that showed how patients with recent pouchitis had significant reductions in specific areas of social, emotional and physical health.