Polypill

Time-restricted eating, particularly among people with underlying metabolic disorders, may confer benefits beyond weight loss, according to a speaker at World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease.

A daily polypill was estimated to be cost-effective for primary CVD prevention among U.S. adults living in historically underserved communities with limited health care access and low income, researchers reported.

Healio and Cardiology Today have compiled the top cardiology headlines of April 2023.

Compared with monotherapy, usual care or placebo, polypills containing three or four low-dose antihypertensive drugs were associated with greater achievement of target BP and more sustained BP lowering, according to a meta-analysis.

A renin-angiotensin system combination polypill to treat high BP was associated with improved adherence and lower all-cause mortality and CV event rates vs. taking multiple pills, researchers reported.

A pill containing antihypertensives and a statin, with or without aspirin, was associated with reduced functional decline, but not reduced cognitive decline, in those aged 65 years and older, researchers reported in JAMA Neurology.

CHICAGO — An ultra-low-dose four-drug quad therapy may improve BP control among patients with hypertension, with no increased safety risk, compared with angiotensin receptor blocker monotherapy, according to a small, first-in-U.S. study.

The European Society of Cardiology Congress was held Aug. 26 to 29 in Barcelona, Spain, and online, having an in-person component for the first time since 2019.

Polypill with aspirin, atorvastatin and ramipril vs. usual care for secondary prevention in patients with MI.

In older adults, a polypill containing aspirin, an ACE inhibitor and a statin within 6 months after myocardial infarction lowered the risk for major adverse CV events compared with usual care, according to results of the SECURE trial.