Polymerase Chain Reaction

Researchers in Brazil identified new echocardiographic parameters and biomarkers prognostic of poor cardiac event-free survival among patients with chronic Chagas disease, which affects up to 7 million worldwide.

An intervention requiring that infectious diseases approve testing for Clostridioides difficile infection increased the appropriateness of testing for hospital-onset C. difficile and lowered the positive testing rate by more than 50%.

The FDA has granted 501(k) clearance and a Clinical Laboratory Improvement Amendments waiver for a polymerase chain reaction diagnostic test to detect sexually transmitted infections in women, according to a press release.

Published results showed a preoperative polymerase chain reaction test with advice about minimizing the risk of SARS-CoV-2 in conjunction with a COVID-free pathway may be safe for patients undergoing hip and knee arthroplasty.

TAMPA, Fla. — Results showed polymerase chain reaction testing may detect a spectrum of bacterial DNA species and allow for targeted treatment and prevention of surgical site infections in orthopedic surgery prior to signs of infection.

Rapid bedside testing is faster than standard centralized laboratory polymerase chain reaction testing for COVID-19 and may improve infection control in the hospital, according to data published in The Lancet Respiratory Medicine.

Multiplex polymerase chain reaction, which uses polymerase chain reaction to simultaneously amplify several different next-generation DNA sequences, had 25.6% sensitivity when performed using Musculoskeletal Infection Society criteria for aspirate or tissue samples collected during 93 revision primary total joint arthroplasties and 77 primary total joint arthroplasties, according to study results.