Percutaneous Coronary Intervention
ULTIMATE: IVUS-guided PCI superior to angiography guidance at 3 years
In patients undergoing PCI with a drug-eluting stent, those whose procedures were guided by IVUS had less target vessel failure at 3 years than those whose procedures were guided by angiography, new data from the ULTIMATE trial showed.
Intact coronary flow reserve may not signify appropriate PCI deferral: DEFINE-FLOW
Among patients with coronary artery lesions, medically treated vessels with abnormal fractional flow reserve but intact coronary flow reserve did not have noninferior outcomes vs. vessels with normal FFR and coronary flow reserve.
Shorter DAPT post-PCI noninferior to longer duration in high bleeding risk
Dual antiplatelet therapy for 1 month or 3 months was noninferior to a 12-month duration with regard to all-cause mortality and MI in patients with high bleeding risk undergoing PCI, researchers found.
Patients with STEMI, COVID-19 represent ‘unique and high-risk’ population
Initial outcomes from the North American COVID-19 STEMI Registry provide a snapshot of the characteristics, presentation, treatment strategies and clinical outcomes of patients with STEMI and confirmed COVID-19.
Ticagrelor monotherapy reduces bleeding, does not impact ischemia after PCI for STEMI
Among patients with STEMI who underwent PCI with an ultrathin bioresorbable polymer sirolimus-eluting stent, switching to ticagrelor monotherapy after 3 months reduced bleeding risk, according to the TICO-STEMI trial.
PCI safe for treatment of nonflow-limiting vulnerable plaques: PROSPECT ABSORB
Among patients with nonflow-limiting vulnerable plaques, PCI with a bioresorbable vascular scaffold was safe and was linked to favorable long-term outcomes, according to the pilot PROSPECT ABSORB trial presented at the virtual TCT Connect.
Decline in radiation during CTO PCI could reflect improvements in X-ray systems
Radiation dose during chronic total occlusion PCI decreased between 2012 and 2020 and may be attributed to the use of newer X-ray systems, according to a research letter published in Circulation: Cardiovascular Interventions.
Procedural MI rates during revascularization vary widely based on definition
In two trials comparing outcomes of PCI with CABG, rates of procedural MI varied greatly depending on which definition was used, according to two analyses published in the Journal of the American College of Cardiology.
FDA expands indication for DES to include patients with high bleeding risk
Medtronic announced that the FDA approved an expanded indication for a drug-eluting stent to include patients with high bleeding risk who take dual antiplatelet therapy for 1 month after PCI.
In younger patients with acute MI, cardiogenic shock, women more often die in hospital
Women hospitalized with acute MI and cardiogenic shock may undergo less aggressive treatment and have higher rates of in-hospital mortality compared with men, researchers reported.