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Pelabresib

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December 27, 2023
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VIDEO: TRANSFORM-1, MANIFEST-2 herald ‘exciting time’ for myelofibrosis patients

In this video, Lindsay A.M. Rein, MD, discussed the TRANSFORM-1 and MANIFEST-2 trials into combination therapies in myelofibrosis, both of which were presented at the ASH Annual Meeting and Exposition.

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December 21, 2023
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VIDEO: Ruxolitinib plus pelabresib shows promise in MANIFEST-2 study

In this video, John Mascarenhas, MD, discussed the MANIFEST-2 study into combination therapies in myelofibrosis treatment, which was presented at the ASH Annual Meeting and Exposition.

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December 20, 2023
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VIDEO: TRANSFORM-1, MANIFEST-2 studies probe combo therapies in myelofibrosis

In this video, Aaron T. Gerds, MD, MS, discussed the TRANSFORM-1 and MANIFEST-2 trials into combination therapies in myelofibrosis, both of which were presented at the ASH Annual Meeting and Exposition.

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November 22, 2023
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Pelabresib reduces spleen volume, symptoms related to myelofibrosis

The combination of pelabresib plus ruxolitinib significantly increased the proportion of patients with myelofibrosis who achieved a clinically meaningful reduction in spleen volume, according to the agent’s manufacturer.

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June 21, 2023
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VIDEO: Pelabresib can control platelet counts in essential thrombocythemia

In this video, Aaron T. Gerds, MD, MS, discussed the backstory behind a study presented at ASCO Annual Meeting, examining the effect of the BET inhibitor pelabresib on patients with essential thrombocythemia.