Pegcetacoplan

The Committee for Medicinal Products for Human Use of the European Medicines Agency confirmed its negative opinion on the marketing authorization application for intravitreal pegcetacoplan for geographic atrophy.

Pegcetacoplan may be a more effective treatment option than avacincaptad pegol for reducing geographic atrophy lesion growth in patients with age-related macular degeneration.

Sobi and Apellis Pharmaceuticals Inc. announced results from the phase 3 Valiant study showing the drug pegcetacoplan reduced proteinuria and stabilized eGFR compared to placebo in patients with glomerulopathy or glomerulonephritis.

SEATTLE — In this video, Eleonora M. Lad, MD, PhD, discusses presentations from the ARVO annual meeting on real-world use of faricimab and the use of pegcetacoplan in the treatment of geographic atrophy.

The Committee for Medicinal Products for Human Use of the European Medicines Agency issued a negative opinion on the marketing authorization application for pegcetacoplan for the treatment of geographic atrophy.

PARK CITY, Utah — In this Healio Video Perspective from Clinical Trials at the Summit, Dilsher S. Dhoot, MD, discusses the functional benefits of pegcetacoplan in patients with geographic atrophy.

Intravitreal pegcetacoplan was associated with delayed atrophy of retinal pigment epithelium and photoreceptors among patients with geographic atrophy secondary to age-related macular degeneration, according to research.

SEATTLE — In this Healio Video Perspective from the ARVO meeting, Jaclyn L. Kovach, MD, discusses the beneficial effects on macular function of continuous pegcetacoplan treatment in geographic atrophy.

SEATTLE — In this Healio Video Perspective from the ARVO meeting, Ashkan M. Abbey, MD, discusses efficacy and safety data for pegcetacoplan for geographic atrophy treatment at 36 months.

Durga S. Borkar, MD, MMCi, assistant professor of ophthalmology and director of clinical data science at Duke University Eye Center, discusses recent FDA approvals that have been useful in the treatment of geographic atrophy.