Pediatric Oncology
Caregivers of childhood cancer survivors express hesitancy on COVID vaccination
Many caregivers expressed hesitancy to vaccinate themselves and their children who had cancer against COVID-19, according to study results published in Pediatric Blood & Cancer.
Chemotherapy-free regimen benefits children with acute promyelocytic leukemia
Children with acute promyelocytic leukemia achieved survival benefit with an all-trans retinoic acid and arsenic trioxide chemotherapy-free regimen, according to study results published in JAMA Oncology.
Clinicians often don’t recognize parent challenges in therapeutic relationships
Many parents of children with cancer experienced challenges in the therapeutic relationship with their child’s treating oncologist, according to study results published in JAMA Network Open.
Out-of-spec CAR-T appears safe, effective for younger patients with ALL
B-cell acute lymphoblastic leukemia is the most common type of cancer among children.
Younger Hispanic/Latinx patients face access barriers to CAR-T clinical trials
Younger Hispanic/Latinx patients face many barriers that may limit timely access to chimeric antigen receptor T-cell therapy trials for relapsed or refractory B-cell acute lymphoblastic leukemia, according to retrospective study results.
FDA grants rare pediatric disease designation to IMX-110 for rhabdomyosarcoma
The FDA granted rare pediatric disease designation to IMX-110 for treatment of children with rhabdomyosarcoma.
Researchers uncover new subtype of pediatric AML defined by UBTF tandem duplications
Upstream binding transcription factor tandem duplications, or UBTF-TDs, identified through integrated genomic analysis represent a new subtype of acute myeloid leukemia that previously had no known oncogenic driver, study results showed.
Ibrutinib plus chemoimmunotherapy confers durable responses in younger patients with CLL
Most patients with chronic lymphocytic leukemia who received ibrutinib plus fludarabine, cyclophosphamide and rituximab continued to maintain deep responses after longer-term follow-up, results of a single arm, phase 2 trial showed.
Task force focuses on quality-of-life issues ‘most relevant to our AYAs’ with cancer
Cancer in adolescents and young adults has become an important area of focus in oncology research.
Preterm birth drug given to millions of women may increase cancer risk in offspring
The offspring of mothers who received 17-hydroxyprogesterone caproate during pregnancy may face nearly double the risk for cancer compared with those who were not exposed, according to a recent study.