Pediatric Oncology

Younger patients with diffuse midline glioma experienced prolonged clinical improvement after receiving an investigational chimeric antigen receptor T-cell therapy, study results demonstrated.

Acute lymphoblastic leukemia molecular subtypes and prognosis appeared associated with genetic ancestry, suggesting a possible genetic basis for racial and ethnic disparities in ALL, according to a study in JAMA Oncology.

Besides making sure each foot lands in front of the other, there isn’t much you can do during a 26.2-mile run other than let your mind wander.

Among children diagnosed with acute lymphoblastic leukemia, Latinos without minimal residual disease had a higher likelihood of relapse than their white counterparts, according to study results.

Younger patients with acute lymphoblastic leukemia who do not respond to CD19-directed chimeric antigen receptor T-cell therapy exhibit certain gene regulation patterns that may be associated with treatment resistance, study results show.

Children with cancer who reside in low- and- middle-income countries had a higher risk for mortality due to any cause than those in high-income countries during the first 9 months of the COVID-19 pandemic, according to study results.

The Research to Accelerate Cures and Equity Act led to an increase in required pediatric studies for recently approved cancer therapies within the first year of the act’s implementation, according to study results.

Clinical trials play an important role in developing and evaluating potential new cancer therapies.

The FDA’s approval of tisagenlecleucel in 2017 resulted in an explosion of research into chimeric antigen receptor T-cell therapies.

The COVID-19 pandemic substantially affected the pediatric oncology workforce, leading to physical, psychological and financial strain, according to results of a survey study published in Cancer.