Pediatric Oncology
‘Substantial’ contributions: More than 20% of patients participate in cancer research
More than 20% of patients with cancer participate in some form of clinical study, and that number is considered a “floor” estimate, according to study results published in Journal of Clinical Oncology.
Tool may predict premature menopause among childhood cancer survivors
A multi-institutional team of researchers created a statistical model capable of predicting the risk for premature menopause among women who survived childhood cancer.
FDA grants Ojemda accelerated approval for children with advanced low-grade brain cancer
The FDA granted accelerated approval to Ojemda for the treatment of certain children with relapsed or refractory low-grade glioma.
Childhood cancer survivors face ‘numerous socioeconomic challenges’
The future of pediatric oncology should place a special emphasis on addressing socioeconomic difficulties that childhood cancer survivors face, according to study data published in JAMA Pediatrics.
Childhood cancer survivors at greater risk for death after major cardiovascular event
Childhood cancer survivors appeared significantly more likely than the general public to die after a major cardiovascular event, according to study results.
COVID-19 diagnosis results in frequent treatment delays among younger patients with ALL
A COVID-19 diagnosis led to a delay in receiving chemotherapy among younger patients with acute lymphoblastic leukemia or lymphoblastic lymphoma, results from a retrospective analysis published in JAMA Network Open showed.
New guidelines say risk classification ‘paramount’ in treating children with neuroblastoma
Determining risk classifications of children with neuroblastoma is “paramount” to optimizing their care, the chair of the first National Comprehensive Cancer Network guidelines panel on the disease, told Healio.
Studies ‘urgently needed’ to understand social factors in blood cancer disparities
Social determinants of health for children and young adults with leukemia and lymphoma must be researched as much as the diseases themselves to improve care, according to a presenter at ASH Annual Meeting and Exposition.
Using pharmacogenomics to guide induction may reduce racial disparities in pediatric AML
Outcomes among children with acute myeloid leukemia treated with high-dose cytarabine-based regimens did not vary by race, according to study results presented at ASH Annual Meeting and Exposition.
FDA expands pediatric solid tumor indication for Rozlytrek, approves new oral formulation
The FDA granted accelerated approval to entrectinib for infants aged 1 month and older who have solid tumors that harbor neurotrophic tyrosine receptor kinase, or NTRK, gene fusion for whom there are no effective treatments.