Pediatric Oncology

Overweight and obesity appeared significantly associated with neurocognitive impairment during long-term follow-up of individuals who received chemotherapy for childhood acute lymphoblastic leukemia, according to a study published in Cancer.

American Association for Cancer Research presented its AACR Team Science Award to the St. Baldrick’s Foundation-Stand Up To Cancer Pediatric Cancer Dream Team.

Childhood brain tumor survivors have a high prevalence of significant weight gain, overweight and obesity, and changes in BMI may indicate hypothalamic-pituitary dysfunction, according to a study published in Journal of Clinical Oncology.

The FDA approved crizotinib for treatment of certain patients with systemic anaplastic large cell lymphoma.

U.S. childhood cancer survivors had worse long-term survival outcomes than U.K. survivors, which suggests they may have undergone more intensive treatment, according to study results published in Journal of the National Cancer Institute.

An investigational chimeric antigen receptor T-cell therapy showed antitumor activity among patients with relapsed or refractory B-cell acute lymphoblastic leukemia, according to data presented at the virtual ASH Annual Meeting and Exposition.

Young patients with B-cell acute lymphoblastic leukemia had shorter RFS and EFS if they received blinatumomab before chimeric antigen receptor T-cell therapy, according to results presented at the virtual ASH Annual Meeting and Exposition.

So-called “chemo brain” is a functionally limiting and frustrating consequence of curative treatment for cancer.

Children undergoing hematopoietic stem cell transplants for cancer had higher rates of transplant-related mortality if they lived in a poorer neighborhood, according to results of a study published in Blood.

Although Hodgkin lymphoma is a highly curable form of pediatric cancer, treatment often results in life-threatening or debilitating long-term adverse effects.