Paravalvular Regurgitation

The fifth generation of a balloon-expandable transcatheter aortic valve replacement system was associated with lower rates of paravalvular leak and lower mean gradients compared with predecessor systems, researchers reported.

SAN FRANCISCO — New 1-year data show a novel system for transcatheter aortic valve replacement was safe and effective for adults with symptomatic severe aortic regurgitation at high surgical risk, a speaker reported at TCT 2023.

In the PORTICO NG study of a next-generation transcatheter aortic valve replacement system, there were no cases of moderate or greater paravalvular leak at 30 days, researchers reported at Cardiovascular Research Technologies.

Researchers in China reported successful transcatheter aortic valve replacements using a novel repositionable and retrievable self-expanding valve in 10 patients with severe symptomatic aortic stenosis.

In a real-world setting, a next-generation self-expanding transcatheter aortic valve replacement system showed improved commissural alignment and target implant depth compared with a prior system, researchers reported at PCR London Valves.

BOSTON — Transcatheter aortic valve replacement with the self-expanding Acurate neo device was similar to the balloon-expandable Sapien 3 device in clinical outcomes at 3 years, according to new data from the SCOPE I trial.

Early European use of the Lotus Edge transcatheter aortic valve replacement system demonstrated good short-term safety and efficacy and low rates of paravalvular leak, according to research presented at the virtual TCT Connect.