Pancreatitis

ATLANTA — Plozasiran provided sustained reduction in triglycerides, apolipoprotein C-III and remnant cholesterol out to 48 weeks for patients with severe hypertriglyceridemia, a speaker reported.

The FDA granted accelerated approval to ponatinib with chemotherapy for the treatment of adults with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia, according to a press release.

A new ACG guideline published in The American Journal of Gastroenterology underscored that early management “is essential” to prevent complications such as organ failure and pancreatic necrosis in patients with acute pancreatitis.

Adults with type 2 diabetes who use GLP-1 receptor agonists do not have an increased short-term risk for pancreatic cancer, according to findings published in JAMA Network Open.

Upfront endoscopic necrosectomy performed at the index intervention resulted in fewer reinterventions compared with a step-up treatment approach among patients with infected necrotizing pancreatitis and fully encapsulated collections.

Researchers identified multiple predictors of opioid overdose after an opioid prescription for chronic pain in a new study published in CMAJ.

Use of glucagon-like peptide 1 agonists for weight loss compared with bupropion-naltrexone was associated with an increased risk for pancreatitis, gastroparesis and bowel obstruction but not biliary disease, researchers reported in JAMA.

Elevated serum triglyceride levels were associated with severity of acute pancreatitis and risk for related complications, including organ failure, among patients with nonalcoholic fatty liver disease, according to data.

From pancreatitis complications to the impact of long COVID, FDA updates to gender disparity in pancreatic cancer, Healio has been at the forefront of coverage for pancreatic disorders in 2023. What have you missed this year?

CHICAGO — Immediate direct endoscopic necrosectomy significantly reduced the number of reinterventions and decreased length of hospital stay compared with a step-up approach in patients with infected necrotizing pancreatitis.