Pancreatic Ductal Adenocarcinoma

An irinotecan liposome injection regimen improved OS compared with standard chemotherapy among untreated patients with metastatic pancreatic ductal adenocarcinoma, according to the agent’s manufacturer.

Adjuvant chemotherapy with modified FOLFIRINOX resulted in significantly longer survival vs. gemcitabine among patients with previously resected pancreatic ductal adenocarcinoma, according to 5-year data from a randomized phase 3 study.

Fecal microbiota-based screening may help with early detection of pancreatic ductal adenocarcinoma, according to a study published in Gut.

The FDA granted orphan drug designation to nadunolimab for the treatment of pancreatic cancer.

Gastric cancer populations that show higher rates of phosphorylated signal transducer and activator of transcription 3 were more likely to have a shorter medial overall survival rate , according to data from a three phase 3 clinical trials presented at ASCO.

A liquid biopsy has shown promise for the early detection and staging of pancreatic ductal adenocarcinoma.

The FDA granted fast track designation to liposomal irinotecan as part of a first-line combination for the treatment of adults with previously untreated, unresectable, locally advanced and metastatic pancreatic ductal adenocarcinoma.

Neoadjuvant therapy-induced sarcopenia in patients who underwent neoadjuvant therapy for pancreatic ductal adenocarcinoma correlated with increased disease recurrence and overall mortality, and reduced overall survival, according to a presentation from Digestive Disease Week.

Increases in the proportion of patients diagnosed with pancreatic cancer at an earlier stage and younger age may be due to improvements in early detection and diagnosis, according to study results published in Journal of National Cancer Institute.

Frequent and early onset of venous thromboembolism are associated with decreased progression-free survival and overall survival among patients diagnosed with pancreatic ductal adenocarcinoma, according to study results.