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Pancreatic Cancer

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June 17, 2022
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VIDEO: Niraparib-ipilimumab maintenance prevents advanced pancreatic cancer progression

VIDEO: Niraparib-ipilimumab maintenance prevents advanced pancreatic cancer progression

In this video, Kim A. Reiss, MD, discussed the results of a randomized phase 1b/2 study of niraparib plus nivolumab or ipilimumab in patients with advanced pancreatic cancer, which were presented in a poster session at ASCO2022.

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June 17, 2022
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VIDEO: Chemotherapy retains some activity after pancreatic cancer progression on rucaparib

VIDEO: Chemotherapy retains some activity after pancreatic cancer progression on rucaparib

In this video, Timothy Brown, MD, discussed the results of his study on treatment outcomes of patients with platinum-sensitive BRCA or PALB2-mutated pancreatic cancer who have been treated with and progressed on rucaparib.

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June 17, 2022
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VIDEO: Blood-based immune biomarkers help identify pancreatic cancer chemoimmunotherapies

VIDEO: Blood-based immune biomarkers help identify pancreatic cancer chemoimmunotherapies

In this video, Robert Vonderheide, MD, DPhil, discussed the results of the phase 2 randomized study of chemoimmunotherapy for patients with metastatic pancreatic cancer.

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June 15, 2022
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Targetable landscape in pancreatic cancer varies greatly by KRAS status

Targetable landscape in pancreatic cancer varies greatly by <i>KRAS</i> status

CHICAGO — Potentially targetable oncogenic rearrangements are more prevalent among patients with KRAS wild-type pancreatic cancer than those with KRAS-mutated disease, according to study results presented at ASCO Annual Meeting.

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June 03, 2022
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Nimotuzumab plus gemcitabine prolongs survival in KRAS wild-type pancreatic cancer

Nimotuzumab plus gemcitabine prolongs survival in <i>KRAS</i> wild-type pancreatic cancer

CHICAGO — The addition of nimotuzumab to gemcitabine prolonged OS and PFS among patients with KRAS wild-type locally advanced or metastatic pancreatic cancer, according to randomized phase 3 study results presented at ASCO Annual Meeting.

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June 02, 2022
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T-cell receptor gene therapy induces response in metastatic pancreatic cancer

T-cell receptor gene therapy induces response in metastatic pancreatic cancer

A woman with metastatic pancreatic cancer attained a 72% partial response with T-cell receptor gene therapy, according to a report published in The New England Journal of Medicine.

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May 27, 2022
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Top in GI: Gallstone disease and pancreatic cancer; new eosinophilic esophagitis drug

Top in GI: Gallstone disease and pancreatic cancer; new eosinophilic esophagitis drug

A presenter at Digestive Disease Week reported that gallstone disease may be a predictor of pancreatic cancer.

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May 16, 2022
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Gallstone disease may be predictor of pancreatic cancer

Gallstone disease may be predictor of pancreatic cancer

Patients with pancreatic ductal adenocarcinoma were six times more likely to have had cholelithiasis or cholecystitis in the year before diagnosis compared with the general population, according to data presented at Digestive Disease Week.

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May 10, 2022
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Neoadjuvant chemoradiotherapy extends OS vs. upfront surgery in pancreatic cancer subsets

Neoadjuvant chemoradiotherapy extends OS vs. upfront surgery in pancreatic cancer subsets

Neoadjuvant gemcitabine-based chemoradiotherapy prolonged OS compared with upfront surgery among patients with resectable and borderline resectable pancreatic cancer, according to phase 3 study results in Journal of Clinical Oncology.

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May 03, 2022
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FDA grants breakthrough device designation for endoscopic ultrasound device

FDA grants breakthrough device designation for endoscopic ultrasound device

Limaca Medical announced it has received breakthrough device designation from the FDA for its Precision-GI endoscopic ultrasound biopsy device, according to a company press release.

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