Ovarian Cancer

Certain occupations — including accountancy, hairdressing, sales and sewing — may be associated with increased risk for ovarian cancer, according to study results published in Occupational and Environmental Medicine.

CHICAGO — Mirvetuximab soravtansine-gynx extended survival of women with platinum-resistant ovarian cancer and high folate receptor-alpha expression, according to a study that compared the agent with investigator’s choice of chemotherapy.

CHICAGO — First-line chemotherapy plus bevacizumab and durvalumab — followed by maintenance durvalumab, bevacizumab and olaparib — extended PFS compared with standard of care for women with non-BRCA-mutated advanced ovarian cancer.

First-degree relatives of individuals with pancreatic ductal adenocarcinoma who harbored certain cancer-associated pathogenic germline variants had significantly higher risk for developing several cancer types, study results showed.

Mirvetuximab soravtansine-gynx conferred a 33% reduction in risk for death compared with chemotherapy for women with folate receptor alpha-positive platinum-resistant ovarian cancer, according to topline data from the agent’s manufacturer.

Whole-exome sequencing identified carriers of predisposition genes for hereditary breast and ovarian cancer or Lynch syndrome who, under current guidelines, would not have qualified for genetic testing, according to study results.

Niraparib did not significantly extend OS among women with recurrent ovarian cancer, according to long-term follow-up results of the ENGOT-OV16/NOVA trial presented at Society of Gynecologic Oncology Annual Meeting on Women’s Cancer.

Neoadjuvant therapy with olaparib showed feasibility for women with germline-mutant ovarian cancer, according to results of the NOW trial presented at Society of Gynecologic Oncology Annual Meeting on Women’s Cancer.

Mailing HPV self-sampling kits to women who are overdue for cervical cancer screening was cost-effective in increasing screening uptake compared with usual care, according to an economic evaluation published in JAMA Network Open.