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Ovarian Cancer

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December 01, 2021
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Mirvetuximab soravtansine active in previously treated ovarian cancer

Mirvetuximab soravtansine active in previously treated ovarian cancer

Mirvetuximab soravtansine induced confirmed objective response in about one-third of women with folate receptor alpha-high platinum-resistant ovarian cancer who previously received bevacizumab, according to the agent’s manufacturer.

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November 30, 2021
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FDA approves Cytalux to identify ovarian cancer lesions during surgery

FDA approves Cytalux to identify ovarian cancer lesions during surgery

The FDA approved the imaging drug pafolacianine to help surgeons identify ovarian cancer lesions.

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November 02, 2021
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Neoadjuvant chemotherapy may be optimal first-line treatment in advanced ovarian cancer

Neoadjuvant chemotherapy may be optimal first-line treatment in advanced ovarian cancer

Increased use of neoadjuvant chemotherapy appeared associated with improvements in short-term mortality without sacrificing long-term survival in ovarian cancer, according to a comparative effectiveness research study in JAMA Oncology.

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October 28, 2021
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FDA grants fast track designation to nemvaleukin alfa for ovarian cancer

FDA grants fast track designation to nemvaleukin alfa for ovarian cancer

The FDA granted fast track designation to nemvaleukin alfa as part of combination therapy for treatment of platinum-resistant ovarian cancer, according to the agent’s manufacturer.

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October 15, 2021
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Next-generation sequencing improves OS in ovarian cancer

New data have linked next-generation sequencing with improved overall survival in ovarian cancer, according to a presenter at the virtual ASCO Annual Meeting.

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October 01, 2021
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Germline BRCA testing underutilized in ovarian cancer

Even among insured patients, germline BRCA testing is underutilized in women with newly diagnosed ovarian cancer, according to a study presented at the virtual ASCO Annual Meeting.

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September 22, 2021
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T-cell receptor therapy ‘definitely effective’ for metastatic solid tumors

T-cell receptor therapy ‘definitely effective’ for metastatic solid tumors

More than a third of patients with solid tumors showed evidence of antitumor response after treatment with ADP-A2M4CD8, according to data presented at the virtual ESMO Congress.

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September 15, 2021
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FDA clears IND application for T-cell receptor therapy to treat epithelial cancers

FDA clears IND application for T-cell receptor therapy to treat epithelial cancers

The FDA cleared an investigational new drug application for a T-cell receptor therapy designed to treat adults with solid epithelial cancers that express Kita-Kyushu lung cancer antigen 1.

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August 31, 2021
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FDA clears IND application for hormone receptor-directed CAR-T to treat ovarian cancer

FDA clears IND application for hormone receptor-directed CAR-T to treat ovarian cancer

The FDA cleared an investigational new drug application for a chimeric antigen receptor T-cell therapy designed to treat women with relapsed epithelial ovarian cancer.

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August 21, 2021
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FDA grants fast track designation to IN10018 for ovarian cancer

The FDA granted fast track designation to IN10018 for treatment of platinum-resistant ovarian cancer.

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