Osteoporosis

In 2019, Healio readers were interested in fertility preservation for men on testosterone therapy, the wonders of metformin, possible associations between statins and diabetes, a new osteoporosis drug and more. 

Faster increases in bone turnover during the menopause transition and greater bone turnover during early postmenopause are risk factors for fracture, even among women with relatively preserved bone mineral density, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Patients who were obese or smokers who underwent surgical treatment for distal radius fractures experienced excellent radiographic and functional outcomes postoperatively at 1 year, according to published results.

ATLANTA — Romosozumab increases bone mineral density among patients with osteoporosis across different levels of renal function, according to a presenter at ACR/ARP 2019.

Older adults who discontinue denosumab are at greater risk for major osteoporotic fractures and multiple vertebral fractures than those who persist with treatment, according to findings from a real-world database analysis published in Bone.

ATLANTA — The 2019 iteration of the ACR/ARP Great Debate tackled the issue of whether anabolic therapies are appropriate for patients with glucocorticoid-induced osteoporosis.

Postmenopausal women who report sleeping less than 5 hours per night are more likely to develop low bone mineral density at all major sites and are at increased risk for osteoporosis at the hip and spine, according to findings published in the Journal of Bone and Mineral Research.

Elderly patients with atrial fibrillation who were prescribed direct oral anticoagulants had significantly lower risk for osteoporotic fractures than patients who were prescribed vitamin K antagonists such as warfarin, researchers reported.

Individuals prescribed high-dose statin therapy to manage cardiovascular risk are more likely to receive a diagnosis of osteoporosis compared with those prescribed a low-dose statin or no therapy, according to findings from a database analysis published in Annals of Rheumatic Diseases.

The American Association of Clinical Endocrinologists joined the International Osteoporosis Foundation in support of World Osteoporosis Day on Sunday, calling on health care providers to make osteoporosis and fracture prevention a priority in daily clinical practice, according to a press release.