Osteoporosis

SAN DIEGO — Results presented at the American Academy of Orthopaedic Surgeons Annual Meeting showed patients with a prior history of osteoporosis may not be contraindicated for a cementless total knee replacement.

Older adults eating an energy-reduced Mediterranean diet and partaking in a physical activity intervention had higher bone mineral density at the lumbar spine at 3 years than those eating an ad libitum Mediterranean diet, researchers wrote.

Adults with COPD who used inhaled corticosteroids for more than 24 months faced higher risks for diabetes, osteoporosis, pneumonia, cataracts and fractures than those with less than 4 months’ use, according to study data.

The FDA has approved two new denosumab biosimilars that are interchangeable with the reference medications Prolia and Xgeva, according to an industry press release.

Three risk assessment tools struggled to detect osteoporosis based on bone mineral density T-scores among women aged 50 to 64 years, researchers reported in a study published in JAMA Network Open.

Multivitamin and cocoa extract supplements do not protect against clinical fractures for older adults, according to data published in the Journal of Bone and Mineral Research.

The FDA has approved two new biosimilars of denosumab for all indications of the reference medications Prolia and Xgeva, according to a press release from Celltrion.

Women with osteoporosis have at least a 50% chance of reaching their target bone mineral density at 3 years if they have a BMD T-score of at least –2.8 at the total hip or –3.1 at the lumbar spine at baseline, according to study findings.

The FDA recently removed semaglutide from its drug shortage list, which has not been considered commercially available since early 2022.

Machine learning may be able to identify older adults most at risk for major adverse cardiovascular events by assessing abdominal aortic calcification in vertebral fracture assessment images, according to study data.