Osteoarthritis

Using MRIs to grade articular pathologies can help identify knees suitable for osteoarthritis trials, as well as those without cartilage damage for which treatment is not indicated, according to data published in Arthritis Care & Research.

A new blood test may offer a more accurate way to track and predict the progression of knee osteoarthritis than current approaches, according to a press release from Duke Health.

Patients with knee osteoarthritis and self-reported knee instability benefit more from education and supervised exercise compared with those without instability, according to data published in Arthritis Care & Research.

KOLOA, Hawaii — In a presentation at Orthopedics Today Hawaii, Jason L. Dragoo, MD, discussed different types of biologics and how these can be used in the treatment of orthopedic conditions.

Despite similar outcomes following endovascular thrombectomy anterior large vessel ischemic stroke, patients with osteoarthritis were 22.5% less likely to undergo EVT compared with those without it, researchers reported.

Solutions for halting osteoarthritis progression and avoiding need for joint replacement remain elusive, but new therapy options, including a novel injection, made headlines in 2022.

Bone size and trabecular disorganization appear to increase with osteophyte formation and joint space narrowing, while volumetric bone mineral density decreases, according to data published in Arthritis Research & Therapy.

Repeat injections of the Wnt pathway inhibitor lorecivivint appears to have slowed the decline of medial joint space width in knee osteoarthritis, according to interim results from a long-term extension trial released by Biosplice.

PHILADELPHIA — Denosumab successfully induces structural modifications patients with active erosive hand osteoarthritis, according to data presented at ACR Convergence 2022.

PHILADELPHIA — A daily glucocorticoid dose higher than 2.5 mg may lead to irreversible bone mineral density loss regardless of intervention with osteoporosis medications, according to data presented at ACR Convergence 2022.