Osteoarthritis

SAN DIEGO — Romosozumab is superior to denosumab for increasing bone mineral density in the spine at 12 months among chronic glucocorticoid users with osteoporosis at high fracture risk, according to data presented at ACR Convergence 2023.

SAN DIEGO — A single injection of TLC599, a liposomal formulation of dexamethasone sodium phosphate, bested placebo for osteoarthritis knee pain over 24 weeks, while a second injection extended benefits to week 52, according to data.

Intra-articular injections of autologous adipose-derived stem cells or adipose-derived stromal vascular fraction significantly improve pain and function in knee osteoarthritis, according to data published in Arthritis Research & Therapy.

In a Healio video exclusive, Leonard Calabrese, DO, chief medical editor of Healio Rheumatology, offered a breakdown of the October issue, including the cover story which delved into the topic of individualized precision medicine.

Patients with osteoarthritis who undergo arthroscopic partial meniscectomy appear to demonstrate greater OARSI score progression via osteophytes, but not Kellgren-Lawrence grades, according to data published in Arthritis Care & Research.

For patients with diseases such as lupus or rheumatoid arthritis who take low-dose drugs at lower frequencies, the relief afforded by over-the-counter drugs such as ibuprofen and naproxen can be a boon.

Patients with osteoarthritis who experience neck pain lasting longer than 1 year have a significant increased risk for all-cause mortality, according to data published in Arthritis Research & Therapy.

Patients with rheumatoid arthritis or osteoarthritis in rural areas are less likely to report in-person health care use, including physician visits and diagnostic tests, vs. those in urban areas, according to data.

Among older adults enrolled in an osteoarthritis cohort, those with foot symptoms such as pain and stiffness demonstrated a higher risk for death vs. those without foot symptoms, according to data published in Arthritis Care & Research.

Patients with intra-articular mineralization demonstrate a two-times higher likelihood of having frequent knee pain, as well as more intermittent or constant pain, according to data published in Arthritis & Rheumatology.