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Optic Neuropathy

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May 07, 2024
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VIDEO: Optogenetic therapy shows vision improvements, safety at 12 months

SEATTLE — In this Healio Video Perspective from the ARVO meeting, Allen C. Ho, MD, FASRS, discusses 12-month data on MCO-010 optogenetic therapy for patients with retinitis pigmentosa.

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May 07, 2024
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Woman presents with unilateral, painless vision loss

A 57-year-old woman was transferred to Lahey Hospital and Medical Center emergency department from a community hospital for an ophthalmology evaluation due to acute, painless vision loss in the left eye upon wakening that morning.

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March 25, 2024
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Lumevoq shows sustained efficacy, safety 4 years after one-time LHON treatment

Lumevoq demonstrated sustained efficacy and a positive safety profile at 4 years after a one-time injection of the gene therapy in patients with Leber hereditary optic neuropathy, according to a press release from GenSight Biologics.

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January 26, 2024
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More focus needed on optic nerve to diagnose severe glaucoma

WAILEA, Hawaii — Clinicians should look more closely at the optic nerve to diagnose cases of severe glaucoma, according to a speaker at Hawaiian Eye 2024.

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April 24, 2023
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Lumevoq demonstrates sustained improvement of BCVA up to 5 years in LHON

BOSTON — Results from the long-term RESTORE study show patients with Leber hereditary optic neuropathy with ND4 mutation who were treated with Lumevoq had sustained improvement of best-corrected visual acuity in both eyes.

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April 06, 2023
8 min read
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Man referred for acute unilateral vision loss upon waking

A 55-year-old man at Tufts Medical Center for hypovolemic shock due to a gastrointestinal hemorrhage was referred to the inpatient ophthalmology consult service for left eye acute painless inferior visual field loss upon waking.

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March 14, 2023
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Real-world data show positive results for Tepezza in dysthyroid optic neuropathy

An analysis of real-world data showed that Tepezza helped improve visual acuity in patients with dysthyroid optic neuropathy, according to a press release.

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March 13, 2023
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Lumevoq gene therapy shows sustained efficacy, safety at 3 years in phase 3 LHON trial

A phase 3 clinical trial demonstrated positive 3-year results for bilateral intravitreal injection of Lumevoq gene therapy, with statistically significant visual acuity improvements from baseline in both treated eyes.

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September 23, 2022
7 min read
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Boy presents with decreased vision after accidental eye trauma

A 7-year-old boy was referred to the neuro-ophthalmology clinic at the New England Eye Center for evaluation of decreased vision in the right eye.

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September 02, 2022
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Woman presents with progressive left eye proptosis, upper lid edema

A 41-year-old woman was referred to the neuro-ophthalmology service at the New England Eye Center for left-sided proptosis, left upper lid edema and progressively worsening vision in the left eye for about 5 months.

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