Opioid
Use of genetic variants to predict opioid use disorder risk may lead to inaccurate results
Candidate genetic variants included in a genetic risk algorithm may not meet standards of reasonable clinical efficacy in identifying opioid use disorder risk, according to a study published in JAMA Network Open.
Purdue Pharma, Sackler family to pay $7.4 billion settlement in opioid lawsuits
Purdue Pharma and its owners have agreed to pay up to $7.4 billion in a new settlement to lawsuits regarding their role in the opioid epidemic, the attorneys general of over a dozen states announced.
Opioid awareness, Part 2: Stomping the stigma and a mom’s view, with Cammie Wolf Rice
In this episode, guest Cammie Wolf Rice discusses the opioid crisis, how it impacted her life and family and her foundation’s mission to combating the epidemic and spreading awareness.
Approach reduces pain, opioid demand among people with pancreatic cancer
The delivery of transvascular energy reduced pain and improved quality of life within 7 days among patients with pancreatic cancer, according to a topline data announcement.
More than half of patients with rheumatic, musculoskeletal disease use OTC supplements
More than 54% of patients with rheumatic and musculoskeletal diseases report daily use of over-the-counter supplements, with “considerable” intake alongside pain relievers, according to data published in Rheumatology Advances in Practice.
FDA requires manufacturers facilitate return of unused opioids
FDA has amended its Risk Evaluation and Mitigation Strategy to require that opioid manufacturers provide pharmacies and dispensaries with materials to facilitate the return of unused opioid analgesics, according to a press release.
FDA approves new dose for abuse-deterrent oxycodone
The FDA approved RoxyBond 10 mg immediate-release tablet for the management of pain requiring an opioid analgesic for which there are no adequate alternative treatments, according to a press release from the manufacturer.
Community-engaged intervention reduces polysubstance overdose deaths by 37%
A community coalition-engaged intervention led to a statistically significant reduction in overdose deaths involving any opioid and psychostimulants other than cocaine, according to a study published in JAMA Network Open.
Significant risks associated with filling opioid prescription after ophthalmic surgery
Filling an opioid prescription after ophthalmic surgery was associated with higher rates of hospitalization, overdose, abuse or dependency, and mortality, according to a study published in Ophthalmology.
Opioid awareness: Stigma, intervention and resources, with David A. Fiellin, MD, Part 1
In this episode, host Hansa Bhargava, MD, discusses opioid awareness, the stigma surrounding the opioid crisis and the resources for intervention with David A. Fiellin, MD.