Oligometastatic Disease
Metastasis-directed radiation therapy may be ‘paradigm shift’ in advanced pancreatic cancer
The addition of comprehensive metastasis-directed radiation therapy to chemotherapy improved outcomes for patients with oligometastatic pancreatic ductal adenocarcinoma, according to results of a randomized phase 2 basket trial.
Serial radiation therapy safe, effective for oligometastatic kidney cancer
Sequential radiotherapy to defer systemic therapy appeared to be a feasible strategy with encouraging PFS and OS among select patients with oligometastatic renal cell carcinoma, according to a study published in The Lancet Oncology.
Single-fraction SBRT ‘a one-stop, knockout punch’ for oligometastatic lung tumors
Single-fraction stereotactic body radiation therapy appeared safe and effective for patients with up to three oligometastatic lung tumors, according to results of the phase 2 SAFRON II trial presented at the virtual ASTRO Annual Meeting.
Precision and uncertainty
I am currently reading a fascinating book — The Perfectionists: How Precision Engineers Created the Modern World, by Simon Winchester.