Obstructive Sleep Apnea

In older men, the sleep breathing impairment index definition of combined insomnia-obstructive sleep apnea predicted incident diabetes, according to results published in Annals of the American Thoracic Society.

BOSTON — Editors of Annals of Internal Medicine compiled a list of studies published over the past year that they said have important implications for internal medicine physicians.

Tirzepatide improved obstructive sleep apnea symptoms compared with placebo among adults with obesity, according to results from the SURMOUNT-OSA trials.

Adults with moderate to severe obstructive sleep apnea and obesity had reductions in sleep apnea severity at 1 year with 10 mg or 15 mg of tirzepatide, according to topline results from two phase 3 trials.

DENVER — In adults with multiple sclerosis, obstructive sleep apnea increases brain atrophy independent of obesity, a common comorbidity, according to a poster at the American Academy of Neurology annual meeting.

Hypoglossal nerve stimulation reduced obstructive sleep apnea severity; however, this outcome was less likely among those with higher BMIs and those who slept in supine position, according to study results.

Among patients with melanoma, untreated moderate to severe obstructive sleep apnea increased the risk for poor long-term prognosis of skin cancer, according to results published in CHEST.

Patients with obstructive sleep apnea who achieved upper airway collapsibility improvement with a drug administered via nasal spray also had lower disease severity after use of the spray, according to study results.

Adding on endotype-informed targeted combination therapies to oral appliance therapy helped reduce obstructive sleep apnea severity, according to results published in Annals of the American Thoracic Society.

Healio has compiled the most-read news in pulmonology posted in February.