Obesity

In a phase 2a trial of patients with obesity-related HF with preserved ejection fraction, a novel controlled metabolic accelerator was associated with weight loss at 3 months compared with placebo.

Decreases in body weight and HbA1c induced by GLP-1 receptor agonists and other diabetes drugs can reduce the risk for cardiometabolic complications for adults newly diagnosed with type 2 diabetes, researchers reported.

A county-level assessment of deaths from cardio-kidney-metabolic disease and social determinants of health revealed that particular determinants are more or less important in different U.S. regions, researchers reported in JAMA.

Hormone therapy use markedly declined among postmenopausal women of all ages, races and ethnicities in the U.S. during the past 2 decades, according to findings published in JAMA Health Forum.

A recently proposed U.S. Senate bill aims to crack down on social media influencers and others online who make misleading comments about pharmaceutical drugs.

Adults with lower cognitive scores before kidney transplantation had similar kidney function, hospital length of stay and readmission and death rates as those with higher pre-transplant scores, according to study data.

Adolescent and young adult women who initiated the etonogestrel contraceptive implant experienced small weight changes over 3 years similar to women who received depot medroxyprogesterone acetate, researchers reported.

Semaglutide was shown to reduce hidradenitis suppurativa flares in patients with obesity, according to a study presented at the European Academy of Dermatology and Venereology meeting.

Women with obesity and atherosclerotic CVD without diabetes experience fewer CV events vs. men enrolled in the SELECT trial; however, semaglutide was linked to significant reductions in CV events regardless of sex, a speaker reported.

Novo Nordisk announced that monlunabant, a novel small molecule oral cannabinoid receptor 1 inverse agonist, was associated with weight loss in a phase 2a study of people with obesity and metabolic syndrome.