Obesity

Women with obesity and atherosclerotic CVD without diabetes experience fewer CV events vs. men enrolled in the SELECT trial; however, semaglutide was linked to significant reductions in CV events regardless of sex, a speaker reported.

Novo Nordisk announced that monlunabant, a novel small molecule oral cannabinoid receptor 1 inverse agonist, was associated with weight loss in a phase 2a study of people with obesity and metabolic syndrome.

BMI in the overweight or obese range for both women and men during preconception or early pregnancy was linked to time to pregnancy success and miscarriage risk, according to study results published in JAMA Network Open.

Adults with type 1 diabetes using either semaglutide or tirzepatide off-label had greater decreases in body weight and HbA1c than those not treated with either medication, according to a speaker.

Among patients with Barrett’s esophagus, every 5 kg/m2 increase in BMI was associated with up to a 6% relative increase in the risk for malignant progression, according to a systematic review and meta-analysis.

Excessive abdominal fat was tied to chronic pain across multiple sites, particularly in women, an analysis published in Regional Anesthesia & Pain Medicine showed.

Use of glucagon-like peptide-1 receptor agonists was associated with a reduced risk for progression to cirrhosis and other complications in patients with metabolic dysfunction-associated steatotic liver disease and diabetes, data showed.

Asthma increased the need for respiratory support in COVID-19 patients, whereas metabolic syndrome raised the risk for severe COVID-19, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.

In a first-in-human study, a novel oral amylin and GLP-1 receptor coagonist was safe and tolerable and lowered weight compared with placebo at 12 weeks in patients with obesity, researchers reported.

ORLANDO, Fla. — For individuals hospitalized with intracerebral hemorrhage, increased caloric intake that led to an increase in weight was associated with higher odds of survival after 3 months, according to a poster.