Obesity

SEATTLE — In this video exclusive, Jonathan D. Leffert, MD, talks with Karl Nadolsky, DO, FACE, DABOM, about the drawbacks of using BMI and the importance of addressing weight stigma and bias when diagnosing and treating obesity.

Although an estimated 45 million Americans will try a diet each year, roughly 90% of people who lose weight end up gaining it back.

Treatment with the melanocortin-4 receptor agonist setmelanotide reduced hyperphagia and led to improvements in emotional well-being among children and adults with Bardet-Biedl syndrome, according to study findings.

SAN DIEGO — ACP has launched a new initiative to improve equitable access to obesity care through physician education, advocacy and partnerships.

Bariatric surgery may significantly lower the risk for obesity-related cancers, including breast, colon, liver, pancreatic, ovarian and thyroid, in patients with obesity.

Adults with overweight or obesity and type 2 diabetes achieved a mean weight loss of more than 13% after taking either 10 mg or 15 mg of tirzepatide for 72 weeks, according to topline results from the SURMOUNT-2 trial.

Bariatric surgery was linked to a decreased risk for major adverse cardiovascular events and all-cause mortality among patients with nonalcoholic fatty liver disease and obesity, according to results in JAMA Network Open.

People with a genetic risk factor for childhood obesity have increased likelihood of developing most subtypes of type 2 diabetes as adults, according to findings from a Mendelian randomization published in Diabetologia.

An increasing number of studies are reporting that testosterone therapy may not only normalize testosterone levels for men, but may also provide cardiometabolic benefits.

More than one-third of adults receiving tirzepatide in clinical trials experience gastrointestinal adverse events, but adverse events leading to drug discontinuation were rare, according to study data.