Obesity

Despite some observational evidence, drinking light or moderate amounts of alcohol may not reduce one’s risk for type 2 diabetes or obesity, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

In this edition, CAR-T trial for leukemia paused after patient death; obesity may increase risk for blood cancer; new CAR T-cell therapies ‘waiting’ for patients with leukemia and more.

The 2018 introduction of calorie labels to restaurant menus appears to have yielded a net reduction in caloric intake of 20 to 60 calories per meal among Americans, potentially reducing risk for obesity-associated cancers.

SAN DIEGO — Adults with overweight or obesity lost up to 18.7% of their body weight at 46 weeks with a glucagon/GLP-1 dual agonist, according to a speaker.

Endoscopic sleeve gastroplasty was more effective for weight loss than lifestyle modification alone in patients with nonalcoholic steatohepatitis and obesity, according to a speaker at EASL Congress.

In adults with obesity and obstructive sleep apnea, bariatric surgery was associated with reduced risk for major adverse CV events compared with no surgery, researchers reported.

SAN DIEGO — Adults with obesity and type 2 diabetes who undergo bariatric or metabolic surgery have a lower HbA1c and greater weight loss than those who did not undergo surgery at 7 and 12 years of follow-up, according to trial data.

SAN DIEGO — Matthias Tschöp, MD, has played a major role in the recent influx of novel therapies for the treatment of diabetes and obesity.

SAN DIEGO — Adults with obesity who received the highest dose of a once-weekly injection of retatrutide lost an average of 24.2% of their body weight at 48 weeks compared with placebo, data from a phase 2 study show.

SAN DIEGO — Adults with obesity and type 2 diabetes achieved a 14.7% weight loss at 72 weeks with 15 mg tirzepatide, according to data from the SURMOUNT-2 trial presented at the American Diabetes Association Scientific Sessions.