Obesity

Editor's Note: This is part 1 of a three-part Healio Exclusive series on navigating statin intolerance.

An intervention involving an energy-reduced Mediterranean diet and physical activity promotion reduced total and visceral fat in adults with overweight or obesity and metabolic symptoms, according to a randomized study.

VANCOUVER, British Columbia — Despite recent changes in nomenclature for metabolic dysfunction-associated steatotic liver disease, an expert here noted that clinical pathways largely remain the same and require reinforcing.

DALLAS — People with obesity who are prescribed anti-obesity medications may need to use the agents for life, but intermittent therapy can still confer health benefits, according to a speaker.

Using physiologically based pharmacokinetic modeling combined with observed clinical data, researchers determined that obesity can lead to reduced exposure and response to antiretroviral drugs.

Although body mass index has long been used in clinical practice, many have recently questioned its effectiveness as a standalone measure for obesity.

DALLAS — Setmelanotide may lower the risk for metabolic syndrome for people with a rare monogenic form of obesity, according to data presented at ObesityWeek.

VANCOUVER, British Columbia — Glucagon-like peptide 1 agonists were significantly less effective for weight loss among patients who underwent laparoscopic sleeve gastrectomy and regained weight, according to a presenter.

VANCOUVER, British Columbia — Tirzepatide 15 mg was associated with the highest degree of weight loss compared with other glucagon-like peptide-1 agonists and placebo, according to a presenter at the ACG Annual Scientific Meeting.