Nonalcoholic Fatty Liver Disease

BOSTON — In pregnant women with cirrhosis, less than 2% had liver decompensation within 1 year after delivery and the odds for decompensation were lower compared with women who were not pregnant with cirrhosis, according to data presented at The Liver Meeting 2019.

BOSTON — A machine learning approach demonstrated a relatively high sensitivity rate for predicting the probability of non-alcoholic steatohepatitis in at-risk patients, according to data presented at The Liver Meeting 2019.

Study results showed that while treatment with Ocaliva for nonalcoholic steatohepatitis led to an increase in LDL cholesterol at 12 weeks, levels reverted to baseline 24 weeks after discontinuation.

Researchers determined that higher liver fat content independent of BMI correlated with an adverse cardio-metabolic risk profile among children.

Cirrhosis, also known as stage 4 fibrosis, is a late stage of scarring in the liver that can result from many chronic liver diseases. Currently, cirrhosis care focuses on management to avoid progression and monitoring in cases that may require liver transplantation.

Gilead Sciences announced a strategic collaboration with Glympse Bio for clinical development of nonalcoholic steatohepatitis therapy, according to a press release.

The FDA granted fast track designation to Terns Pharmaceuticals for TERN-101, an investigational farnesoid X receptor being evaluated for nonalcoholic steatohepatitis, according to a press release.

SAN ANTONIO — The National Liver Congress will convene October 25th, providing a broad scientific program and exhibit of products and services important for all practitioners involved in the care of patients with liver disease.

The injectable hormone tesamorelin reduces liver fat and prevents liver fibrosis in patients living with HIV, suggesting it may provide significant clinical benefits in this population, according to study results published in The Lancet HIV.

CHICAGO — During this year’s North American Society for Pediatric Gastroenterology, Hepatology & Nutrition annual meeting, Mercedes Martinez, MD, from the New York-Presbyterian Columbia University Irving Medical Center in New York, will co-host the Single Topic Symposium on Chronic Liver Disease Management for the Gastroenterologist.