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Nivolumab

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September 16, 2024
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Nivolumab plus ipilimumab offers ‘potential for cure’ in advanced melanoma

Nivolumab plus ipilimumab offers ‘potential for cure’ in advanced melanoma

The addition of nivolumab to ipilimumab conferred a long-term OS benefit for patients with advanced melanoma, according to study results presented at ESMO Congress.

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September 09, 2024
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Perioperative nivolumab improves outcomes in resectable NSCLC

Perioperative nivolumab improves outcomes in resectable NSCLC

Immunotherapy before and after surgery significantly improved EFS compared with neoadjuvant immunotherapy only for patients with resectable non-small cell lung cancer, according to a comparison of results from two randomized phase 3 trials.

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July 19, 2024
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Phase 3 renal cell carcinoma trial misses primary endpoint

Phase 3 renal cell carcinoma trial misses primary endpoint

The addition of nivolumab to low-dose tivozanib did not improve PFS for patients with advanced renal cell carcinoma, according to data from the agent’s manufacturer.

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June 02, 2024
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Neoadjuvant immunotherapy ‘the new standard’ for resectable stage III melanoma

Neoadjuvant immunotherapy ‘the new standard’ for resectable stage III melanoma

CHICAGO — Individuals with resectable stage III melanoma derived significant EFS benefits with neoadjuvant immunotherapy compared with standard treatment, results from a randomized phase 3 trial presented at ASCO Annual Meeting showed.

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June 02, 2024
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‘Practice-changing data’ support first-line immunotherapy combination in colorectal cancer

‘Practice-changing data’ support first-line immunotherapy combination in colorectal cancer

CHICAGO — Combination immunotherapy significantly improved outcomes vs. first-line chemotherapy for patients with microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer, according to study results.

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June 01, 2024
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Targeted induction before immunotherapy shows limited benefit in advanced melanoma

Targeted induction before immunotherapy shows limited benefit in advanced melanoma

CHICAGO — Sequencing encorafenib plus binimetinib with nivolumab and ipilimumab did not delay disease progression in adults with advanced BRAF-mutated melanoma, results from a randomized phase 2 trial showed.

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May 13, 2024
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Phase 3 trial of nivolumab for advanced lung cancer misses primary endpoint

Phase 3 trial of nivolumab for advanced lung cancer misses primary endpoint

A randomized phase 3 trial that evaluated nivolumab with concurrent chemoradiotherapy for certain patients with advanced lung cancer failed to meet its primary endpoint, according to the agent’s manufacturer.

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May 02, 2024
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VIDEO: Coming years may see new approvals in metastatic breast cancer

VIDEO: Coming years may see new approvals in metastatic breast cancer

Healio spoke with Paolo Tarantino, MD, about treatments in the pipeline for metastatic breast cancer.

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March 21, 2024
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Immunotherapy combination improves survival in advanced liver cancer

Immunotherapy combination improves survival in advanced liver cancer

The addition of nivolumab to ipilimumab significantly improved OS among adults with previously untreated advanced hepatocellular carcinoma, according to a release by the agent’s manufacturer.

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March 20, 2024
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VIDEO: Notable PFS improvement from nivolumab plus ipilimumab for colorectal cancer

VIDEO: Notable PFS improvement from nivolumab plus ipilimumab for colorectal cancer

In this video, Afsaneh Barzi, MD, PhD, discusses the results of the CheckMate 8HW study.

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