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Nivolumab

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January 22, 2021
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FDA approves first-line Opdivo-Cabometyx regimen for advanced renal cell carcinoma

FDA approves first-line Opdivo-Cabometyx regimen for advanced renal cell carcinoma

The FDA approved nivolumab in combination with cabozantinib as first-line treatment of patients with advanced renal cell carcinoma, according to a manufacturer-issued press release.

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January 21, 2021
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Gut microbiome a potential biomarker for nivolumab efficacy in advanced gastric cancer

Gut microbiome a potential biomarker for nivolumab efficacy in advanced gastric cancer

The gut microbiome potentially could serve as a biomarker to predict the efficacy of nivolumab among patients with advanced gastric cancer, according to results of the DELIVER trial presented at Gastrointestinal Cancers Symposium.

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January 20, 2021
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FDA grants priority review to Opdivo for gastric, esophageal cancer indications

FDA grants priority review to Opdivo for gastric, esophageal cancer indications

The FDA granted priority review to nivolumab for two gastrointestinal cancer indications, according to the agent’s manufacturer.

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January 13, 2021
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Healio round-up: 2020 game changing lung cancer trials

2020 presented many challenges, including the transformation of conferences and meetings into virtual events.

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January 07, 2021
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Top in hem/onc: New leadership at MD Anderson, Opdivo withdrawn from market

Top in hem/onc: New leadership at MD Anderson, Opdivo withdrawn from market

The University of Texas MD Anderson Cancer Center recently named Welela Tereffe, MD, as its chief medical executive. It was the top story in hematology/oncology last week.

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December 30, 2020
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Bristol Myers Squibb withdraws Opdivo for small cell lung cancer indication

Bristol Myers Squibb withdraws Opdivo for small cell lung cancer indication

Bristol Myers Squibb withdrew nivolumab from the U.S. market for the treatment of patients with small cell lung cancer that progressed after platinum-based chemotherapy and at least one other therapy, according to a press release.

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December 17, 2020
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VIDEO: Post-transplant consolidation with nivolumab, brentuximab shows promise in Hodgkin lymphoma

VIDEO: Post-transplant consolidation with nivolumab, brentuximab shows promise in Hodgkin lymphoma

Consolidation with nivolumab and brentuximab vedotin after autologous hematopoietic cell transplantation showed promise in patients with high-risk Hodgkin lymphoma, according to a presentation at the ASH Annual Meeting and Exposition.

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November 25, 2020
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Addition of SBRT to nivolumab fails to improve outcomes in metastatic head and neck cancer

Addition of SBRT to nivolumab fails to improve outcomes in metastatic head and neck cancer

The addition of stereotactic body radiation therapy to nivolumab did not improve outcomes among a cohort of patients with metastatic head and neck squamous cell carcinoma, according to a study published in Journal of Clinical Oncology.

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November 24, 2020
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Ipilimumab-nivolumab combination effective, safe for angiosarcoma subset

Ipilimumab-nivolumab combination effective, safe for angiosarcoma subset

A quarter of patients with unresectable or metastatic angiosarcoma responded to a combination of ipilimumab and nivolumab, according to results of an analysis presented at the virtual Society for Immunotherapy of Cancer Annual Meeting.

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November 12, 2020
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Continuous nivolumab appears effective, safe in advanced NSCLC

Continuous nivolumab appears effective, safe in advanced NSCLC

Continued nivolumab treatment after 1 year appeared effective and safe for certain patients with advanced non-small cell lung cancer, according to an exploratory analysis of the CheckMate 153 study published in Journal of Clinical Oncology.

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