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March 21, 2025
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Adding cisplatin to radiation fails to extend survival in intermediate-risk cervical cancer

Adding cisplatin to radiation fails to extend survival in intermediate-risk cervical cancer

The addition of concurrent cisplatin to adjuvant radiation therapy conferred no benefit to women with intermediate-risk, early-stage cervical cancer who underwent radical hysterectomy, according to randomized phase 3 study results.

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February 05, 2025
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‘More work to do’ to determine cost-effectiveness of universal Duffy testing

‘More work to do’ to determine cost-effectiveness of universal Duffy testing

SAN DIEGO — Lauren E. Merz, MD, MSc, can still feel both the relief and anger two parents expressed during her first year of medical school at University of Michigan.

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February 04, 2025
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Temozolomide regimen extends survival for people with grade 2 gliomas

Temozolomide regimen extends survival for people with grade 2 gliomas

The addition of temozolomide to radiation therapy prolonged OS for patients with both co-deleted and non-co-deleted grade 2 gliomas, according to study results.

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January 23, 2025
4 min read
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Glucarpidase improves recovery after chemotherapy-induced kidney toxicity

Glucarpidase improves recovery after chemotherapy-induced kidney toxicity

Glucarpidase significantly improved kidney function for patients who developed acute kidney injury from high-dose methotrexate, according to results of a large, multicenter observational study.

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January 14, 2025
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Support tool reduced urine culture tests by 50%

Support tool reduced urine culture tests by 50%

A computerized clinical decision support tool implemented as a diagnostic stewardship intervention led to an approximate 50% decrease in urine culture testing for patients with a urinary catheter, researchers found.

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January 09, 2025
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Combination induces durable responses in advanced multiple myeloma

Combination induces durable responses in advanced multiple myeloma

The combination of talquetamab and teclistamab induced durable responses among patients with relapsed or refractory multiple myeloma, according to phase 1B/phase 2 study results.

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November 08, 2024
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De-escalated adjuvant chemotherapy effective for high-risk retinoblastoma

De-escalated adjuvant chemotherapy effective for high-risk retinoblastoma

A shortened adjuvant chemotherapy regimen improved outcomes for infants with unilateral pathologic high-risk retinoblastoma, according to study results.

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October 18, 2024
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FDA approves Vyloy with chemotherapy for some gastric cancers, approves diagnostic device

FDA approves Vyloy with chemotherapy for some gastric cancers, approves diagnostic device

The FDA approved Vyloy with chemotherapy to treat locally advanced unresectable or metastatic HER2-negative gastric or gastroesophageal junction adenocarcinoma in adults, according to a press release.

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October 18, 2024
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’Reassuring’ findings show eliminating 5-FU bolus in GI cancer does not affect survival

’Reassuring’ findings show eliminating 5-FU bolus in GI cancer does not affect survival

Patients with metastatic gastrointestinal cancer may not need a 5-FU bolus as part of their treatment, according to retrospective study results.

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August 21, 2024
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Tocilizumab taper increases time to relapse vs. abrupt withdrawal in giant cell arteritis

Tocilizumab taper increases time to relapse vs. abrupt withdrawal in giant cell arteritis

Tapering tocilizumab leads to a longer relapse-free period in patients with giant cell arteritis, compared with abrupt discontinuation, according to data published in Seminars in Arthritis and Rheumatism.

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