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Neurofilament Light Chain

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April 25, 2024
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Presence of neurofilament light chain linked to sleep, cognition in Parkinson’s disease

DENVER — Cognitive impairment in Parkinson’s is a mitigating factor for presence of blood-based biomarkers during sleep as indicator of disease progression, according to a poster at the American Academy of Neurology annual meeting.

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January 08, 2024
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Positive results reported in open label extension of novel ALS therapeutic

A clinical-stage biopharmaceutical company has reported new positive data from a 12-month long-term open label extension of the CNM-Au8 treatment arm in the HEALEY ALS Platform Trial.

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November 13, 2023
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Neurofilament light chain predicted confirmed disability worsening at 1 to 2 years in MS

For those with multiple sclerosis, presence of elevated neurofilament light chain biomarkers was associated with symptom progression that predicted clinical disease worsening within 1 to 2 years, according to research from JAMA Neurology.

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October 11, 2023
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Vidofludimus calcium linked to neurofilament light chain reduction in MS

For those with relapsing-remitting multiple sclerosis, treatment with vidofludimus calcium led to reductions in neurofilament light chain biomarkers as early as week 6 compared with placebo, according to a presentation at ECTRIMS 2023.

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September 06, 2023
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Serum neurofilament light chain database effective in estimating pediatric neuro issues

Compared with absolute values, serum neurofilament light chain Z scores were linked to higher effect size metrics and more accurate estimation of persistent neuroaxonal damage in pediatric populations, per data from The Lancet Neurology.