Neonatal Screening

Between 40 and 80 infants are born with severe combined immunodeficiency disorder each year in the United States and Canada. The disease is fatal without bone marrow transplants as infections overwhelm compromised immune systems.

Few studies have evaluated infant and parental outcomes of false-positive results from newborn screening of congenital hypothyroidism, and most studies are low or moderate quality, according to a systematic review.

An updated evidence-based guideline supports global neonatal screening for congenital hypothyroidism to optimize detection, diagnosis, treatment and follow-up of children with the condition.

There was a significant correlation between childhood exposure to nitrogen dioxide and the polygenic risk score for schizophrenia, according to findings published by JAMA Network Open.