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Myeloproliferative Neoplasm

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November 15, 2022
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VIDEO: Understanding the ‘pivotal role’ NF-cappaB plays in myeloproliferative neoplasms

In this video, John O. Mascarenhas, MD, highlighted a presentation that explored the science driving clinical development.

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November 15, 2022
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VIDEO: Myeloproliferative neoplasms treatment may be ‘driven by genomic distinctions’

John O. Mascarenhas, MD, spoke with Healio about a presentation given during the morning session at 14th International Congress on Myeloproliferative Neoplasms.

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November 11, 2022
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VIDEO: New treatments in myeloproliferative neoplasms signal ‘exciting’ time for field

In this video, John O. Mascarenhas, MD, provided an overview of his presentation at 14th International Congress on Myeloproliferative Neoplasms that delved into new treatments, specifically focused on myelofibrosis.

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August 26, 2022
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FDA approves pemigatinib for myeloid/lymphoid neoplasms with FGFR1 rearrangement

The FDA approved pemigatinib for treatment of adults with relapsed or refractory myeloid/lymphoid neoplasms and rearrangement of fibroblast growth factor receptor 1, according to a press release from the agent’s manufacturer.

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June 25, 2022
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Momelotinib improves symptom, spleen responses in symptomatic, anemic myelofibrosis

Aaron T. Gerds, MD, MS, spoke with Healio about the randomized phase 3 MOMENTUM study.

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June 21, 2022
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FDA grants orphan drug designation to TP-3654 for myelofibrosis

The FDA granted orphan drug designation to TP-3654 for the treatment of myelofibrosis.

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June 16, 2022
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Hematocrit levels, white blood cell counts influence thrombosis risk in polycythemia vera

Aaron T. Gerds, MD, MS, spoke with Healio about the REVEAL study, results of which were presented at this year’s European Hematology Association Congress.

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May 24, 2022
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World Trade Center responders have higher burden of mutations linked to blood cancers

First responders to the World Trade Center had higher rates of clonal hematopoiesis-associated mutations than firefighters not exposed to the dust, gases and potential carcinogens at the site, according to a study in Nature Medicine.

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May 20, 2022
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FDA places partial hold on trial for patients with AML, myelodysplastic syndrome

The FDA placed a partial clinical hold on a phase 1 dose-escalation study of a therapy under investigation for certain patients with blood cancer.

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April 26, 2022
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Donor socioeconomic status affects hematopoietic stem cell transplant outcomes

SALT LAKE CITY — Socioeconomic disadvantage among hematopoietic stem cell transplant donors appeared associated with poorer outcomes among transplant recipients, according to study results.

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