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Myelofibrosis

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New Frontiers in the Targeted Treatment of Myelofibrosis

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March 06, 2023
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Incyte to discontinue phase 3 study of parsaclisib plus ruxolitinib for myelofibrosis

A randomized phase 3 study of parsaclisib plus ruxolitinib for adults with myelofibrosis appeared unlikely to meet its primary endpoint and will be discontinued, according to the agents’ manufacturer.

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December 21, 2022
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Pelabresib-ruxolitinib combination reduces spleen volume, symptom score in myelofibrosis

Pelabresib plus ruxolitinib conferred benefit to Janus kinase inhibitor-naive patients with myelofibrosis, according to study results presented at ASH Annual Meeting and Exhibition.

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December 20, 2022
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VIDEO: Momelotinib benefits maintained at 24 weeks in patients with anemic myelofibrosis

NEW ORLEANS — In this video, Aaron T. Gerds, MD, MS, assistant professor at the Cleveland Clinic Taussig Cancer Institute, discusses updated results from the Momentum phase 3 study presented at the ASH Annual Meeting and Exposition.

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December 11, 2022
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Combination reduces spleen length in intermediate-, high-risk myelofibrosis

The combination of ruxolitinib and pegylated interferon alpha-2a exhibited encouraging activity among patients with myelofibrosis who had not previously received either drug, according to study results presented at ASH Annual Meeting and Exposition.

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November 22, 2022
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VIDEO: Case study at Congress on Myeloprolieferative Neoplasms supports data from UK

In this video, Srinivas K. Tantravahi, MBBS, MRCP(UK), discussed a case study, presented at the 14th International Congress on Myeloproliferative Neoplasms, of dizygotic twins.

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November 22, 2022
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VIDEO: Pharmacologic and nonpharmacologic development for myeloproliferative neoplasms

Srinivas K. Tantravahi, MBBS, MRCP(UK), spoke with Healio about both nonpharmacologic interventions and pharmacologic developments for patients with myeloproliferative neoplasms.

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November 18, 2022
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VIDEO: Potential field-changing research at Congress on Myeloproliferative Neoplasms

In this video, Brynn H. Parsegov, PA-C, highlighted two presentations from the 14th International Congress on Myeloproliferative Neoplasms.

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November 17, 2022
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VIDEO: Understanding myeloproliferative neoplasms from a ‘broad lens’ perspective

Healio spoke with Brynn H. Parsegov, PA-C, about a presentation exploring the timing, as well as impact, of diagnosis for myeloproliferative neoplasms.

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November 17, 2022
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VIDEO: Potential in-utero transfer of stem cells may impact future MPN research

In this video, Brynn H. Parsegov, PA-C, discussed a case of fraternal female twins who sequentially presented with JAK2V617F mutation-positive myeloproliferative neoplasms.

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