Myeloablative Conditioning

Myeloablative fludarabine and busulfan conditioning appeared effective for patients with myelofibrosis undergoing allogeneic stem cell transplant, according to results presented at Society of Hematologic Oncology Annual Meeting.

ORLANDO — Myeloablative conditioning before hematopoietic stem cell transplantation conferred a long-term survival advantage compared with reduced-intensity conditioning among patients with acute myeloid leukemia or myelodysplastic syndrome, according to extended follow-up of the randomized phase 3 MAvRIC trial presented at TCT | Transplantation & Cellular Therapy Meetings.

Myeloablative conditioning prior to allogeneic hematopoietic stem cell transplantation may result in improved survival compared with reduced-intensity conditioning for patients with acute myeloid leukemia with genomic evidence of measurable residual disease, according to results of a randomized phase 3 study published in Journal of Clinical Oncology.